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KMID : 0603519990040040187
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Journal of Korean Association of Cancer Prevention
1999 Volume.4 No. 4 p.187 ~ p.195
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The Effect of Phellinus linteus on Leukocytes Chemotaxis in Mouse Transplanted with Sarcoma-180 Tumor Cells
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Cho Hong-Sik
Yoon Jeong-Joong
Lee Yun-Tai
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Abstract
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The purpose of this experiment is to examine the effects Phellinus linteus on leukocyte migration, the number of leukocytes and the cytotoxicity of Phellinus linteus extract against human cancer cell line. The results were as follows; The chemotaxis of leukocytes from Phellinus linteus-treated mice was significantly increased.
The number of leukocytes cells significantly increased in Phellinus linteus-treated tumor-bearing mice.
The cytotoxicity against human cancer cell lines of Phellinus linteus extract was not significant by changed.
According to these results, Phellinus linteus could activate chemotatic leukocytes, increase the number of leukocytes and have no cytotoxic activity on human cell lines.
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KEYWORD
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Leukocytes chemotaxis, Sarcoma-180 cells, Phellinus linteus
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